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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f428372fdcd68ab54f23cab7305654ca1d277e1b30189b33d34846e0d9e244c' 
  AND token = '2S10WSfPt8XY6jG6HUruyezv6IlKm+phV8URx4xgN0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}