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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d91c0a9e90cb4705fa2f23bb4dc7c4310cb2727e64d1ea5124cd8f7754cd03' 
  AND token = 'E5rL88btTaVpIsU0CQn+EaPzmKQCSX20fdq+D0UwNDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}