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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4845a71cca5b80b69559511b8932c7633b6e6904f3da5405d8ab89b2c4ca218' 
  AND token = 'RRJTZlc2e919JfZmbRjlmIS2DIQRb85BnI5GSFdM2s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}